Genes, greens, and homocysteine.

Study of plasma homocysteine, folic acid and vitamin B-12 levels for radiation exposed transplanted solid Ehirlich tumors

Background: Alterations of systemic metabolic parameters are always present vitamins in cancer in addition radiotherapy may increases and complicates these disorders. The analysis of each biochemical metabolic alterations may give more understanding to biochemistry of malignancy   and improving the degree of radiotherapy. The current study aimed to follow up the changes of folate, vitamin B12 a...

Homocysteine Induces Heme Oxygenase-1 Expression via Transcription Factor Nrf2 Activation in HepG2 Cells

Background: Elevated level of plasma homocysteine has been related to various diseases. Patients with hyperhomocysteinemia can develop hepatic steatosis and fibrosis. We hypothesized that oxidative stress induced by homocysteine might play an important role in pathogenesis of liver injury. Also, the cellular response designed to combat oxidative stress is primarily controlled by the transcripti...

Basal Frequency of SNPs from Genes Involved in Homocysteine Metabolism and Coronary Artery Disease Basal Frequency of SNPs from Genes involved in Homocysteine Metabolism and CAD

Homocysteine- and cysteine-mediated growth defect is not associated with induction of oxidative stress response genes in yeast.

Intracellular thiols like cysteine, homocysteine and glutathione play a critical role in the regulation of important cellular processes. Alteration of intracellular thiol concentration results in many diseased states; for instance, elevated levels of homocysteine are considered to be an independent risk factor for cardiovascular disease. Yeast has proved to be an excellent model system for stud...

Serum homocysteine level in vitiligo patients

Background: Vitiligo is a common cutaneous depigmentation disorder caused by the destruction of melanocytes. The exact etiopathogenesis of this disorder is not well known, but a complex of genetic, immunologic, inflammatory, and cytotoxic factors have been implicated. According to reports on the role of vitamin B12 and folic...